While new gene therapies are curing devastating illnesses, they can be some of the most expensive treatments in the world. Our Gene Therapy Solution works as a provision of our stop loss policy to ensure your employees and their family members have coverage for the best possible treatments while protecting your company’s financial security. We don’t stop there. Not only do we cover the treatment, but we also cover the medicalcosts.
By bringing together health services, medical management, and specialty pharmacy expertise, we take a whole-health approach to address your employees’ unique needs, so they can navigate their health experience with confidence and hope.
Breakthrough gene replacement therapies are anticipated to:
in estimated gene therapy costs by 20321
Reach up to
$40 Billion
new gene therapies to receive FDA approval each year by 20262
Include more than
25
in potential cost of a single claim3
Reach more than
$4 Million
Working together to change lives for the better
With over 4,000 gene therapies in line for approval, employers are able to offer employees the best in modern medicine.4
Anthem’s Gene Therapy Solution includes emerging FDA-approved clinical treatments with strong potential for high effectiveness in treating difficult rare conditions.
A whole-health approach to gene therapy treatments
Dedicated care
Dedicated care
Direct access to an Anthem dedicated Nurse Care Manager who develops a tailored approach to each employee’s treatment.
Assistance with travel coordination whenrequired.
Behavioral support
Behavioral support
Proactive anxiety and depression assessments of employees and their covered family members, with referrals to Anthem benefits andprograms.
Digital, telephonic, and in-person behavioral health support through network care providers and programs.*
*The programs require employerelection.
A connected experience
A connected experience
An Anthem Nurse Care Manager collaborates with the employee, their care team, family, and employer throughout thetreatment.
Close monitoring of expectant mothers with babies who test positive for spinal muscular atrophy for faster turn-aroundtimes.
Access to Blue Distinction Centers for GeneTherapy.
Applies to the Gene Therapy Solution that includes an Anthem medical plan.
What is gene therapy?
Gene therapy is an evolving treatment for rare disorders caused by a missing or faulty gene. It may involve addition, inhibition, editing, or functional replacement of a gene. Gene therapies can be one-time treatments and target the genetic root cause of the disease. These treatments are administered in hospitals as infusions, so they fall under medical coverage instead of pharmacy.
Covered therapies for rare and complexconditions
Select each treatment to learn more.
Beqvez™
BeqvezTM
Casgevy™
CasgevyTM
ElevidysTM
ElevidysTM
Hemgenix®
Hemgenix®
Lenmeldy™
LenmeldyTM
Luxturna®
Luxturna®
Lyfgenia™
Lyfgenia™
RoctavianTM
RoctavianTM
Skysona®
Skysona®
Zolgensma®
Zolgensma®
Zynteglo®
Zynteglo®
Beqvez $3.5 million one-timetherapy
Used to treat patients with moderate to severe hemophilia B who are receiving routine prophylaxis, have a current life-threatening bleed, a history of life-threatening bleeds, or repeated serious spontaneous bleeds.
Casgevy $2.2 million one-timetherapy
Used to treat sickle cell disease in patients over the age of 12 with a history of vasoocclusive events (VOEs) and patients with beta thalassemia who need regular blood transfusions.
Elevidys $3 million one-timetherapy
Used to treat patients with Duchenne muscular dystrophy (DMD) with a confirmed mutation in the DMD gene who do not have a preexisting medical reason preventing treatment with this therapy.
Hemgenix $3.5 million one-timetherapy
Used to treat patients over the age of 18 with hemophilia B, a genetic bleeding disorder resulting from missing or insufficient levels of blood clotting Factor IX, a protein needed to produce blood clots and stop bleeding.
Lenmeldy $4.25 million one-timetherapy
Used to treat early onset metachromatic leukodystrophy (MLD) in presymptomatic patients, this gene therapy may yield a lasting preservation of cognition and motor function.
Luxturna $850,000 one-time therapy
Used to treat hereditary retinal dystrophies. This loss of vision, often during childhood or youth, ultimately progresses to complete blindness.
Lyfgenia $3 million one-timetherapy
Used to treat sickle cell disease in patients over the age of 12 with a history of vasoocclusive events (VOEs).
Roctavian $3 million one-timetherapy
Used to treat patients over the age of 18 with hemophilia A, a genetic bleeding disorder. It occurs due to a mutation on the gene which produces Factor VIII (FVIII), a protein that enables blood to clot.
Skysona $3 million one-time therapy
Used to slow the progression of neurologic dysfunction in 4- to 17-year-old boys with early, active cerebral adrenoleukodystrophy (CALD). This progressive, neurodegenerative disease is caused by mutations in the ABCD1 gene.
Zolgensma $2 million one-timetherapy
Used to treat patients with spinal muscular atrophy (SMA), a genetic disease characterized by the progressive loss of motor neurons or nerve cells that control muscle movement.
Zynteglo $2.8 million one-timetherapy
Used to treat beta-thalassemia that requires regular red blood cell transfusions. Beta-thalassemia is a rare blood disorder that causes reduction of hemoglobin and red blood cells.
Anthem continually monitors promising FDA-approved gene therapies to include for coverage and offers financial protection for ASO employers specific to these therapies.
Source: U.S. Food & Drug Administration: fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/approved-cellular-and-gene-therapy-products.
Resources
Learn more about our Gene TherapySolution:
Healthcare Innovation: New Gene Therapies Spark Transformative HealthcareChanges
Healthcare Innovation: Preparing For The Next Wave Of Promising Gene Therapiesarticle
We’re in yourcorner
Together, we can help your employees live longer and healthier lives while helping you successfully manage costs.
1 Institute for Clinical and Economic Review (ICER): Managing the Challenges of Paying for Gene Therapies (April 2024): https://icer.org.
2 Carelon: Q2 2004 CarelonRx Drug and Biologic Pipeline Update (May 23, 2024): carelonrx.com/perspectives/2024-q2-carelon-rx-drug-biologic-pipeline-update.
3 Projection based on retail drug cost and possible additional expenses as a result of receivingtreatment.
4 American Society of Gene + Cell Therapy (ASGCT): Gene, Cell, + RNA Therapy Landscape Report: Q1 2024 (accessed July 2024): asgct.org.
In California Anthem Blue Cross is the trade name of Blue Cross of California, Inc. Also serving California: Anthem Blue Cross Life and Health Insurance Company. In 11 northeastern counties of New York Anthem Blue Cross is the trade name of Anthem HealthChoice Assurance, Inc., and Anthem HealthChoice HMO, Inc., and Anthem Blue Cross HP is the trade name of Anthem HP, LLC. Independent licensees of the Blue Cross Association. Anthem is a registered trademark of Anthem Insurance Companies, Inc.